Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation

Lee, HY; Han, J; Lee, YJ; Kim, MJ; Kwon, WH; Chanda, D; Thoudam, T; Pagire, HS; Pagire, SH; Ahn, JH; Harris, RA; Kim, ES; Lee, IK

Kim, ES (通讯作者),Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Gastroenterol, 130 Dongdeok ro, Daegu 41944, South Korea.;Lee, IK (通讯作者),Kyungpook Natl Univ, Sch Med, Dept Internal Med, 130 Dongdeok ro, Daegu 41944, South Korea.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2023; 15 (2): 439

Abstract

BACKGROUND & AIMS: Despite recent evidence supporting the metabolic plasticity of CD4(+) T cells, it is uncertain whether the metabolic checkpoint......

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