Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection

Klumpp, K; Shimada, T; Allweiss, L; Volz, T; Lutgehetmann, M; Hartman, G; Flores, OA; Lam, AM; Dandri, M

Klumpp, K (reprint author), Novira Therapeut Inc, 3805 Old Easton Rd, Doylestown, PA 18902 USA.

GASTROENTEROLOGY, 2018; 154 (3): 652

Abstract

BACKGROUND & AIMS: NVR3-778 is a capsid assembly modulator in clinical development. We determined the in vivo antiviral efficacy and effects on in......

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