Pharmacological chaperones for the misfolded melanocortin-4 receptor associated with human obesity

Huang, H; Wang, W; Tao, YX

Tao, YX (reprint author), Auburn Univ, Dept Anat Physiol & Pharmacol, Coll Vet Med, 212 Greene Hall, Auburn, AL 36849 USA.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2017; 1863 (10): 2496

Abstract

The melanocortin-4 receptor (MC4R) plays a vital role in regulating energy homeostasis. Mutations in the MC4R cause early -onset severe obesity. The m......

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