6-(4 '-Aryl-1 ',2 ',3 '-triazolyl)-spirostan-3,5-diols and 6-(4 '-Aryl-1 ',2 ',3 '-triazolyl)-7-hydroxyspirosta-1,4-dien-3-ones: Synthesis and analysis of their cytotoxicity

Mironov, ME; Oleshko, OS; Pokrovskii, MA; Rybalova, TV; Pechurov, VK; Pokrovskii, AG; Cheresis, SV; Mishinov, SV; Stupak, VV; Shults, EE

Shults, EE (reprint author), Russian Acad Sci, Siberian Branch, Novosibirsk Inst Organ Chem, Lab Med Chem, Lavrentyev Ave 9, Novosibirsk 630090, Russia.; Shults, EE (reprint author), Novosibirsk State Univ, Pirogova Str 2, Novosibirsk 630090, Russia.

STEROIDS, 2019; 151 ():

Abstract

In an endeavour to develop potent anti-tumor agents from diosgenin, a series of C-6 derived 1,2,3-triazolyl derivatives were designed and synthesized ......

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