Histone deacetylase 3 preferentially binds and collaborates with the transcription factor RUNX1 to repress AML1?ETO?dependent transcription in t(8;21) AML

Guo, C; Li, J; Steinauer, N; Wong, M; Wu, B; Dickson, A; Kalkum, M; Zhang, JS

Zhang, JS (corresponding author), St Louis Univ, Sch Med, Dept Pharmacol & Physiol, St Louis, MO 63104 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2020; 295 (13): 4212

Abstract

In up to 15% of acute myeloid leukemias (AMLs), a recurring chromosomal translocation, termed t(8;21), generates the AML1?eight?twenty-one (ETO) leuke......

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