NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

Waqas, FH; Shehata, M; Elgaher, WAM; Lacour, A; Kurmasheva, N; Begnini, F; Kiib, AE; Dahlmann, J; Chen, CT; Pavlou, A; Poulsen, TB; Merkert, S; Martin, U; Olmer, R; Olagnier, D; Hirsch, AKH; Pleschka, S; Pessler, F

Pessler, F (通讯作者)，TWINCORE Ctr Expt & Clin Infect Res, Res Grp Biomarkers Infect Dis, Hannover, Germany.;Pessler, F (通讯作者)，Helmholtz Ctr Infect Res, Res Grp Biomarkers Infect Dis, Braunschweig, Germany.;Pessler, F (通讯作者)，Ctr Individualised Infect Med, Hannover, Germany.

PLOS PATHOGENS, 2023; 19 (7):

Abstract

Author summaryVirus infections often cause organ damage via excessive inflammation and oxidative stress. The identification of host-directed treatment......

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