Acetylshikonin induces autophagy-dependent apoptosis through the key LKB1-AMPK and PI3K/Akt-regulated mTOR signalling pathways in HL-60 cells

Wu, MD; Zhang, YY; Yi, SY; Sun, BB; Lan, J; Jiang, HM; Hao, GP

Jiang, HM; Hao, GP (通讯作者)，Shandong First Med Univ & Shandong Acad Med Sci, Sch Basic Med Sci, Jinan, Shandong, Peoples R China.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2022; 26 (5): 1606

Abstract

Acetylshikonin (ASK) is a natural naphthoquinone derivative of traditional Chinese medicine Lithospermum erythrorhyzon. It has been reported that ASK ......

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