Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4

Sowalsky, AG; Kissick, HT; Gerrin, SJ; Schaefer, RJ; Xia, Z; Russo, JW; Arredouani, MS; Bubley, GJ; Sanda, MG; Li, W; Ye, HH; Balk, SP

Ye, HH (reprint author), Harvard Med Sch, Boston, MA 02115 USA.; Ye, HH (reprint author), Beth Israel Deaconess Med Ctr, Dept Pathol, 330 Brookline Ave, Boston, MA 02215 USA.; Balk, SP (reprint author), Beth Israel Deaconess Med Ctr, 330 Brookline Ave, Bo

CLINICAL CANCER RESEARCH, 2017; 23 (14): 3823

Abstract

Purpose: The molecular features that account for the distinct histology and aggressive biological behavior of Gleason pattern 4 (Gp4) versus Gp3 prost......

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