Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA)

Lin, SM; Koh, JJ; Aung, TT; Sin, WLW; Lim, FH; Wang, L; Lakshminarayanan, R; Zhou, L; Tan, DTH; Cao, DR; Beuerman, RW; Ren, L; Liu, SP

Ren, L (reprint author), South China Univ Technol, Sch Mat Sci & Engn, Guangzhou 510641, Guangdong, Peoples R China.; Beuerman, RW; Liu, SP (reprint author), Singapore Eye Res Inst, 20 Coll Rd,Discovery Tower Level 6, Singapore 169856, Singapore.; Beuerma

JOURNAL OF MEDICINAL CHEMISTRY, 2017; 60 (14): 6152

Abstract

A new series of semisynthetic flavone-based small molecules mimicking antimicrobial peptides has been designed from natural icaritin to combat drug-re......

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