Evaluation of the Effects of Apatinib on the Pharmacokinetics of Venlafaxine and O-desmethylvenlafaxine in SD Male Rats by UPLC-MS/MS

Bao, SS; Wen, J; Lin, QM; Li, YH; Huang, YG; Zhou, HY; Hu, GX

Zhou, HY; Hu, GX (reprint author), Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Peoples R China.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018; 123 (6): 721

Abstract

The objective of this study was to evaluate the effect of apatinib on the pharmacokinetics of venlafaxine and O-desmethylvenlafaxine in SD rats and th......

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