Quantitative Structure Activity Relationship Studies and Molecular Dynamics Simulations of 2-(Aryloxyacetyl)cyclohexane-1,3-Diones Derivatives as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

Fu, Y; Liu, YX; Yi, KH; Li, MQ; Li, JZ; Ye, F

Ye, F (reprint author), Northeast Agr Univ, Coll Sci, Dept Appl Chem, Harbin, Heilongjiang, Peoples R China.

FRONTIERS IN CHEMISTRY, 2019; 7 ():

Abstract

4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a significant enzyme in the biosynthesis of plastoquinone and tocopherol. Moreover, it is also a potenti......

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