Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

Kivioja, JL; Thanasopoulou, A; Kumar, A; Kontro, M; Yadav, B; Majumder, MM; Javarappa, KK; Eldfors, S; Schwaller, J; Porkka, K; Heckman, CA

Heckman, CA (reprint author), Univ Helsinki, Inst Mol Med Finland, Helsinki Inst Life Sci, Helsinki, Finland.

LEUKEMIA, 2019; 33 (6): 1360

Abstract

Acute myeloid leukemia (AML) with co-occurring NUP98-NSD1 and FLT3-ITD is associated with unfavorable prognosis and represents a particularly challeng......

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