Novel BH4-BCL-2 Domain Antagonists Induce BCL-2-Mediated Apoptosis in Triple-Negative Breast Cancer

Kanakaveti, V; Ramasamy, S; Kanumuri, R; Balasubramanian, V; Saravanan, R; Ezhil, I; Pitani, R; Venkatraman, G; Rayala, SK; Gromiha, MM

Rayala, SK; Gromiha, MM (通讯作者),Indian Inst Technol Madras, Bhupat & Jyoti Mehta Sch Biosci, Dept Biotechnol, Chennai 600036, Tamil Nadu, India.

CANCERS, 2022; 14 (21):

Abstract

Simple Summary Our work has led to the identification of three novel BH4 mimetics, SM216, SM396, and SM949, with nanomolar activities both in vitro an......

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