Elucidation of structure-activity relationship of humulanolides and identification of humulanolide analog as a novel HSP90 inhibitor

Saegusa, J; Osada, Y; Miura, K; Sasazawa, Y; Ogura, A; Takao, K; Simizu, S

Simizu, S (通讯作者),Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, 3-14-1 Hiyoshi, Yokohama, Kanagawa 2238522, Japan.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022; 60 ():

Abstract

Humulanolides are natural products isolated from Asteriscus, and the isolation and total synthesis of many types of humulanolides have been reported. ......

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