Humanised effector-null Fc gamma RIIA antibody inhibits immune complex-mediated proinflammatory responses

Chen, B; Vousden, KA; Naiman, B; Turman, S; Sun, H; Wang, S; Vinall, LMK; Kemp, BP; Kasturiangan, S; Rees, DG; Grant, E; Hinrichs, MJ; Eck, S; DiGiandomenico, A; Borrok, MJ; Ly, N; Xiong, XM; Gonzalez, C; Morehouse, C; Wang, Y; Zhou, YB; Cann, J; Zha

Chen, B; Sims, GP (reprint author), MedImmune LLC, Dept Resp Inflammat & Autoimmun, Gaithersburg, MD 20878 USA.

ANNALS OF THE RHEUMATIC DISEASES, 2019; 78 (2): 228

Abstract

Objective Immune complexes (ICs) play a critical role in the pathology of autoimmune diseases. The aim of this study was to generate and characterise ......

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