Silencing PCBP2 normalizes desmoplastic stroma and improves the antitumor activity of chemotherapy in pancreatic cancer

Li, YK; Zhao, Z; Lin, CY; Liu, YL; Staveley-OCarroll, KF; Li, GF; Cheng, K

Cheng, K (corresponding author), Univ Missouri, Sch Pharm, Div Pharmacol & Pharmaceut Sci, 2464 Charlotte St, Kansas City, MO 64108 USA.

THERANOSTICS, 2021; 11 (5): 2182

Abstract

Rationale: Dense desmoplastic stroma is a fundamental characteristic of pancreatic ductal adenocarcinoma (PDAC) and comprises up to 80% of the tumor m......

Full Text Link