Acquired resistance to BRAF inhibitors is mediated by BRAF splicing variants in BRAF V600E mutation-positive colorectal neuroendocrine carcinoma

Shimizu, Y; Maruyama, K; Suzuki, M; Kawachi, H; Low, SK; Oh-hara, T; Takeuchi, K; Fujita, N; Nagayama, S; Katayama, R

Katayama, R (通讯作者)，Japanese Fdn Canc Res, Canc Chemotherapy Ctr, Koto Ku, 3-8-31 Ariake, Tokyo 1358550, Japan.

CANCER LETTERS, 2022; 543 ():

Abstract

Neuroendocrine carcinomas (NECs), a poorly differentiated subtype of neumendocrine neoplasms, are aggressive and have a poor prognosis. Colorectal neu......

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