The efficacy of selinexor (KPT-330), an XPO1 inhibitor, on non-hematologic cancers: a comprehensive review

Landes, JR; Moore, SA; Bartley, BR; Doan, HQ; Rady, PL; Tyring, SK

Tyring, SK (通讯作者),Univ Texas Hlth Sci Ctr Houston, Dept Dermatol, 6431 Fannin St,MSB Room 1 308, Houston, TX 77070 USA.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023; 149 (5): 2139

Abstract

Purpose Selinexor is a novel XPO1 inhibitor which inhibits the export of tumor suppressor proteins and oncoprotein mRNAs, leading to cell-cycle arrest......

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