ApoE-associated modulation of neuroprotection from A beta-mediated neurodegeneration in transgenic Caenorhabditis elegans

Griffin, EF; Scopel, SE; Stephen, CA; Holzhauer, AC; Vaji, MA; Tuckey, RA; Berkowitz, LA; Caldwell, KA; Caldwell, GA

Caldwell, GA (reprint author), Univ Alabama, Dept Biol Sci, Box 870344, Tuscaloosa, AL 35487 USA.; Caldwell, GA (reprint author), Univ Alabama Birmingham, Sch Med, Nathan Shock Ctr Res Basic Biol Aging, Dept Neurol,Ctr Neurodegenerat & Expt Therapeut, Bir

DISEASE MODELS & MECHANISMS, 2019; 12 (2):

Abstract

Allele-specific distinctions in the human apolipoprotein E (APOE) locus represent the best-characterized genetic predictor of Alzheimer's disease (AD)......

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