The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice

Wei, L; Leibowitz, BJ; Epperly, M; Bi, C; Li, A; Steinman, J; Wipf, P; Li, S; Zhang, L; Greenberger, J; Yu, J

Yu, J (reprint author), Univ Pittsburgh, Sch Med, Dept Pathol, UPMC Hillman Canc Ctr, Pittsburgh, PA 15213 USA.; Yu, J (reprint author), UPMC Hillman Canc Ctr, Dept Radiat Oncol, Pittsburgh, PA 15213 USA.

SCIENTIFIC REPORTS, 2018; 8 ():

Abstract

Total body irradiation (TBI) leads to dose-and tissue-specific lethality. In the current study, we demonstrate that a mitochondrion-targeted nitroxide......

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