DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages

Cobo, I; Tanaka, TN; Mangalhara, KC; Lana, A; Yeang, C; Han, C; Schlachetzki, J; Challcombe, J; Fixsen, BR; Sakai, M; Li, RZ; Fields, H; Mokry, M; Tsai, RG; Bejar, R; Prange, K; de Winther, M; Shadel, GS; Glass, CK

Glass, CK (通讯作者)，Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA.

IMMUNITY, 2022; 55 (8): 1386

Abstract

Deleterious somatic mutations in DNA methyltransferase 3 alpha (DNMT3A) and TET mehtylcytosine dioxygenase 2 (TET2) are associated with clonal expansi......

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