A functional drug re-purposing screening identifies carfilzomib as a drug preventing 17 beta-estradiol: ER alpha signaling and cell proliferation in breast cancer cells

Busonero, C; Leone, S; Klemm, C; Acconcia, F

Acconcia, F (reprint author), Univ Roma Tre, Dept Sci, Sect Biomed Sci & Technol, Viale Guglielmo Marconi 446, I-00146 Rome, Italy.

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2018; 460 (C): 229

Abstract

Most cases of breast cancer (BC) are estrogen receptor cc-positive (ER alpha+) at diagnosis. The presence of ER alpha drives the therapeutic approach ......

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