Deoxyguanosine is a TLR7 agonist

Davenne, T; Bridgeman, A; Rigby, RE; Rehwinkel, J

Rehwinkel, J (reprint author), Univ Oxford, Med Res Council Human Immunol Unit, Med Res Council Weatherall Inst Mol Med, Radcliffe Dept Med, Oxford, England.

EUROPEAN JOURNAL OF IMMUNOLOGY, 2020; 50 (1): 56

Abstract

Toll-like receptor 7 (TLR7) is an innate immune sensor for single-strand RNA (ssRNA). Recent structural analysis revealed that TLR7 has an additional ......

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