Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway

Liang, YM; Zhou, Y; Wang, JL; He, Y

He, Y (通讯作者),Guangxi Med Univ, Dept Geriatr Cardiol, Affiliated Hosp 1, 6 Shuangyong Rd, Nanning 530021, Qingxiu Region, Peoples R China.

IMMUNITY INFLAMMATION AND DISEASE, 2023; 11 (10):

Abstract

BackgroundMyocardial fibrosis is an important factor in the induction and maintenance of atrial fibrillation (AF). Fibromodulin (FMOD) promotes fibrot......

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