Activation of CAR and non-CAR T cells within the tumor microenvironment following CAR T cell therapy

Chen, PH; Lipschitz, M; Weirather, JL; Jacobson, C; Armand, P; Wright, K; Hodi, FS; Roberts, ZJ; Sievers, SA; Rossi, J; Bot, A; Go, W; Rodig, SJ

JCI INSIGHT, 2020; 5 (12):

Abstract

Mechanisms of chimeric antigen receptor (CAR) T cell-mediated antitumor immunity and toxicity remain poorly characterized because few studies examine ......

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