Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosis

Seyedsadr, MS; Weinmann, O; Amorim, A; Ineichen, BV; Egger, M; Mirnajafi-Zadeh, J; Becher, B; Javan, M; Schwab, ME

Javan, M (reprint author), Tarbiat Modares Univ, Dept Physiol, Fac Med Sci, Tehran, Iran.; Schwab, ME (reprint author), Univ Zurich, Brain Res Inst, CH-8057 Zurich, Switzerland.

NEUROBIOLOGY OF DISEASE, 2019; 124 (): 189

Abstract

Multiple sclerosis is an inflammatory disease of the central nervous system (CNS) in which multiple sites of blood-brain barrier (BBB) disruption, foc......

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