Determination of the absolute oral bioavailability of niraparib by simultaneous administration of a C-14-microtracer and therapeutic dose in cancer patients

van Andel, L; Rosing, H; Zhang, Z; Hughes, L; Kansra, V; Sanghvi, M; Tibben, MM; Gebretensae, A; Schellens, JHM; Beijnen, JH

van Andel, L (reprint author), Antoni van Leeuwenhoek Netherlands Canc Inst, Dept Pharm & Pharmacol, POB 90440, NL-1006 BK Amsterdam, Netherlands.; van Andel, L (reprint author), MC Slotervaart, POB 90440, NL-1006 BK Amsterdam, Netherlands.

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018; 81 (1): 39

Abstract

Introduction Niraparib (Zejula (TM)) is a poly(ADP-ribose) polymerase inhibitor recently approved by the US Food and Drug Administration for the maint......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索