Purification, full-length sequencing and genomic origin mapping of eccDNA

Wang, YG; Wang, M; Zhang, Y

Zhang, Y (通讯作者)，Howard Hughes Med Inst, Boston, MA 02115 USA.;Zhang, Y (通讯作者)，Boston Childrens Hosp, Program Cellular & Mol Med, Boston, MA 02115 USA.;Zhang, Y (通讯作者)，Dept Genet, Boston, MA 01960 USA.;Zhang, Y (通讯作者)，Harvard Stem Cell Inst WAB 149G, Boston, MA 02138 USA.

NATURE PROTOCOLS, 2023; 18 (3): 683

Abstract

Extrachromosomal circular DNA (eccDNA) was discovered more than half a century ago. However, its biogenesis and function have just begun to be elucida......

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