Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity

Rodriguez, M; Trevisan, B; Ramamurthy, RM; George, SK; Diaz, J; Alexander, J; Meares, D; Schwahn, DJ; Quilici, DR; Figueroa, J; Gautreaux, M; Farland, A; Atala, A; Doering, CB; Spencer, HT; Porada, CD; Almeida-Porada, G

Almeida-Porada, G (通讯作者)，Wake Forest Sch Med WFSOM, Wake Forest Inst Regenerat Med, Fetal Res & Therapy Program, Winston Salem, NC 27101 USA.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Hemophilia A is the most common X-linked bleeding disorder affecting more than half-a-million individuals worldwide. Persons with severe hemophilia A ......

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