Isophthalic Acid-Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni

Stenzel, K; Chakrabarti, A; Melesina, J; Hansen, FK; Lancelot, J; Herkenhohner, S; Lungerich, B; Marek, M; Romier, C; Pierce, RJ; Sippl, W; Jung, M; Kurz, T

Kurz, T (reprint author), Heinrich Heine Univ Dusseldorf, Inst Pharmazeut & Med Chem, Univ Str 1, D-40225 Dusseldorf, Germany.

ARCHIV DER PHARMAZIE, 2017; 350 (8):

Abstract

Schistosoma mansoni histone deacetylase 8 (SmHDAC8) has been recently identified as a new potential target for the treatment of schistosomiasis. A ser......

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