LPS stimulation stabilizes HIF-1 alpha by enhancing HIF-1 alpha acetylation via the PARP1-SIRT1 and ACLY-Tip60 pathways in macrophages

Chen, Q; Cui, K; Zhao, ZQ; Xu, X; Liu, YT; Shen, YN; Chen, F; Mai, KS; Ai, QH

Ai, QH (通讯作者)，Ocean Univ China, Key Lab Aquaculture Nutr & Feed, Minist Agr & Rural Affairs, 5 Yushan Rd, Qingdao 266003, Shandong, Peoples R China.;Ai, QH (通讯作者)，Ocean Univ China, Key Lab Mariculture, Minist Educ, 5 Yushan Rd, Qingdao 266003, Shandong, Peoples R China.

FASEB JOURNAL, 2022; 36 (7):

Abstract

Hypoxia and inflammatory mediators stabilize hypoxia-inducible factor (HIF)-1 alpha through posttranslational modifications, such as phosphorylation a......

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