Differential m(6)A, m(6)A(m), and m(1)A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

Wei, JB; Liu, FG; Lu, ZK; Fei, QL; Ai, YX; He, PC; Shi, HL; Cui, XL; Su, R; Klungland, A; Jia, GF; Chen, JJ; He, C

He, C (reprint author), Univ Chicago, Dept Biochem & Mol Biol, Dept Chem, 929 East 57 St, Chicago, IL 60637 USA.; He, C (reprint author), Univ Chicago, Inst Biophys Dynam, 929 East 57 St, Chicago, IL 60637 USA.; He, C (reprint author), Univ Chicago, Howar

MOLECULAR CELL, 2018; 71 (6): 973

Abstract

FTO, the first RNA demethylase discovered, mediates the demethylation of internal N-6-methyladenosine (m(6)A) and N-6, 2-O-dimethyladenosine (m(6)A(m)......

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