Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

Teraoka, Y; Uchida, T; Imamura, M; Osawa, M; Tsuge, M; Abe-Chayama, H; Hayes, CN; Makokha, GN; Aikata, H; Miki, D; Ochi, H; Ishida, Y; Tateno, C; Chayama, K

Chayama, K (reprint author), Hiroshima Univ, Inst Biomed & Hlth Sci, Dept Gastroenterol & Metab, Minami Ku, 1-2-3 Kasumi, Hiroshima 7348551, Japan.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018; 500 (2): 152

Abstract

Patients with chronic hepatitis C virus (HCV) infection who have failed to respond to direct-acting antiviral (DAA) treatment often acquire drug resis......

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