Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer

Wei, JL; Fang, M; Fu, ZX; Zhang, SR; Guo, JB; Wang, R; Lv, ZB; Xiong, YF

Fu, ZX (reprint author), Chongqing Med Univ, Affiliated Hosp 1, Dept Gastrointestinal Surg, Chongqing 400016, Peoples R China.

ONCOTARGET, 2017; 8 (30): 49318

Abstract

Sestrin 2 is a conserved antioxidant protein that reduces reactive oxygen species (ROS) and inhibits mammalian target of rapamycin complex 1 (mTORC1).......

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