Synthesis of NSC 106084 and NSC 14778 and evaluation of their DNMT inhibitory activity

Leroy, M; Melin, L; LaPlante, SR; Medina-Franco, JL; Gagnon, A

Gagnon, A (reprint author), Univ Quebec Montreal, Dept Chim, CP 8888, Montreal, PQ H3C 3P8, Canada.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019; 29 (6): 826

Abstract

DNA methylation is an epigenetic modification that is performed by DNA methyltransferases (DNMTs) and that leads to the transfer of a methyl group fro......

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