The anti-DKK1 antibody DKN-01 as an immunomodulatory combination partner for the treatment of cancer

Wall, JA; Klempner, SJ; Arend, RC

Arend, RC (corresponding author), Univ Alabama Birmingham, Dept Obstet & Gynecol, Div Gynecol Oncol, 619 19th St South 176F Room 10250, Birmingham, AL 35249 USA.; Klempner, SJ (corresponding author), Massachusetts Gen Hosp, Canc Ctr, 55 Fruit St Yawkey 7-E, Boston, MA 02114 USA.

EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020; 29 (7): 639

Abstract

Introduction The Wnt/beta-catenin pathway is a complex signaling pathway known to be dysregulated in several cancers; Dickkopf-1 (Dkk1) is an inhibito......

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