Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity

Jang, YG; Choi, Y; Jun, K; Chung, J

Chung, J (corresponding author), Seoul Natl Univ, Inst Mol Biol & Genet, Seoul 08826, South Korea.; Chung, J (corresponding author), Seoul Natl Univ, Sch Biol Sci, Seoul 08826, South Korea.

MOLECULES AND CELLS, 2020; 43 (8): 705

Abstract

While the growth factors like insulin initiate a signaling cascade to induce conformational changes in the mechanistic target of rapamycin complex 1 (......

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