Sequence of alpha PD-1 relative to local tumor irradiation determines the induction of abscopal antitumor immune responses

Wei, J; Montalvo-Ortiz, W; Yu, LL; Krasco, A; Ebstein, S; Cortez, C; Lowy, I; Murphy, AJ; Sleeman, MA; Skokos, D

Skokos, D (corresponding author), Regeneron Pharmaceut, 777 Old Saw Mill River Rd, Tarrytown, NY 10591 USA.

SCIENCE IMMUNOLOGY, 2021; 6 (58):

Abstract

Although radiotherapy has been used for over a century to locally control tumor growth, alone it rarely induces an abscopal response or systemic antit......

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