Programmable RNA detection with CRISPR-Cas12a

Rananaware, SR; Vesco, EK; Shoemaker, GM; Anekar, SS; Sandoval, LSW; Meister, KS; Macaluso, NC; Nguyen, LT; Jain, PK

Jain, PK (通讯作者)，Univ Florida, Dept Mol Genet & Microbiol, Gainesville, FL 32611 USA.;Jain, PK (通讯作者)，Univ Florida, UF Hlth Canc Ctr, Gainesville, FL 32611 USA.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Cas12a, a CRISPR-associated protein complex, has an inherent ability to cleave DNA substrates and is utilized in diagnostic tools to identify DNA mole......

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