Albumin downregulates Klotho in tubular cells

Fernandez-Fernandez, B; Izquierdo, MC; Valino-Rivas, L; Nastou, D; Sanz, AB; Ortiz, A; Sanchez-Nino, MD

Ortiz, A; Sanchez-Nino, MD (reprint author), Univ Autonoma Madrid, Fdn Jimenez Diaz, IIS, Dept Nephrol, Madrid, Spain.; Sanchez-Nino, MD (reprint author), IRSIN, Fdn Renal Inigo Alvarez Toledo, Madrid, Spain.; Ortiz, A; Sanchez-Nino, MD (reprint author),

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2018; 33 (10): 1712

Abstract

Background. Kidney tubular cells are the main sources of Klotho, a protein with phosphaturic action. Genetic Klotho deficiency causes premature cardio......

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