Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia

Narayanan, P; Curtis, BR; Shen, LJ; Schneider, E; Tami, JA; Paz, S; Burel, SA; Tai, LJ; Machemer, T; Kwoh, TJ; Xia, ST; Shattil, SJ; Witztum, JL; Engelhardt, JA; Henry, SP; Monia, BP; Hughes, SG

Narayanan, P (corresponding author), Ionis Pharmaceut Inc, 2855 Gazelle Court, Carlsbad, CA 92010 USA.

NUCLEIC ACID THERAPEUTICS, 2020; 30 (2): 94

Abstract

Inotersen, a 2 '-O-methoxyethyl (2 '-MOE) phosphorothioate antisense oligonucleotide, reduced disease progression and improved quality of life in pati......

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