Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling

Kim, E; Jang, J; Park, JG; Kim, KH; Yoon, K; Yoo, BC; Cho, JY

Cho, JY (corresponding author), Sungkyunkwan Univ, Dept Integrat Biotechnol, Biomed Inst Convergence SKKU BICS, Suwon 16419, South Korea.; Yoo, BC (corresponding author), Natl Canc Ctr, Div Translat Sci, Res Inst, Goyang 10408, South Korea.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020; 21 (9):

Abstract

Protein arginine methyltransferase 1 (PRMT1) is the most predominant PRMT and is type I, meaning it generates monomethylarginine and asymmetric dimeth......

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