Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC: ALK- and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition

Urbanska, EM; Sorensen, JB; Melchior, LC; Costa, JC; Santoni-Rugiu, E

Urbanska, EM (corresponding author), Copenhagen Univ Hosp, Rigshosp, Dept Oncol, DK-2100 Copenhagen, Denmark.; Santoni-Rugiu, E (corresponding author), Copenhagen Univ Hosp, Rigshosp, Dept Pathol, DK-2100 Copenhagen, Denmark.; Santoni-Rugiu, E (corresponding author), Univ Copenhagen, Biotech Res & Innovat Ctr BRIC, DK-2200 Copenhagen, Denmark.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020; 21 (8):

Abstract

Anaplastic lymphoma-kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is prone to developing heterogeneous, only partly known mechanisms of r......

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