Deletions in FLT-3 juxtamembrane domain define a new class of pathogenic mutations: case report and systematic analysis

Young, DJ; Nguyen, B; Zhu, RQ; Seo, JS; Li, L; Levis, MJ; Pratz, KW; Duffield, AS; Small, D

Small, D (corresponding author), Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, CRB1 Room 251,1650 Orleans St, Baltimore, MD 21231 USA.

BLOOD ADVANCES, 2021; 5 (9): 2285

Abstract

The FMS-like tyrosine kinase 3 (FLT-3) is the most frequently mutated gene in acute myeloid leukemia (AML), a high-risk feature, and now the target of......

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