The balance of interleukin (IL)-6, IL-6 center dot soluble IL-6 receptor (sIL-6R), and IL-6 center dot sIL-6R center dot sgp130 complexes allows simultaneous classic and trans-signaling

Baran, P; Hansen, S; Waetzig, GH; Akbarzadeh, M; Lamertz, L; Huber, HJ; Ahmadian, MR; Moll, JM; Scheller, J

Scheller, J (reprint author), Univ Str 1, D-40225 Dusseldorf, Germany.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2018; 293 (18): 6762

Abstract

Interleukin (IL-)6 is the major pro-inflammatory cytokine within the IL-6 family. IL-6 signals via glycoprotein 130 (gp130) and the membrane-bound or ......

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