Tegsedi (Inotersen): An Antisense Oligonucleotide Approved for the Treatment of Adult Patients with Hereditary Transthyretin Amyloidosis

Gales, L

Gales, L (reprint author), I3S Inst Invest & Inovacao Saude, Rua Alfredo Allen 208, Porto, Portugal.; Gales, L (reprint author), Univ Porto, IBMC, Rua Alfredo Allen 208, Porto, Portugal.; Gales, L (reprint author), Univ Porto, ICBAS, Rua Jorge Viterbo Fer

PHARMACEUTICALS, 2019; 12 (2):

Abstract

Tegsedi (Inotersen) is a chemically modified antisense oligonucleotide that inhibits the hepatic production of transthyretin (TTR). Several single-poi......

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