Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project

Merino, DM; Mcshane, LM; Fabrizio, D; Funari, V; Chen, SJ; White, JR; Wenz, P; Baden, J; Barrett, JC; Chaudhary, R; Chen, L; Chen, WJ; Cheng, JH; Cyanam, D; Dickey, JS; Gupta, V; Hellmann, M; Helman, E; Li, YL; Maas, J; Papin, A; Patidar, R; Quinn, KJ; Rizvi, N; Tae, H; Ward, C; Xie, MC; Zehir, A; Zhao, C; Dietel, M; Stenzinger, A; Stewart, M; Allen, J

Merino, DM (corresponding author), Friends Canc Res, Washington, DC 20036 USA.

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020; 8 (1):

Abstract

Background Tumor mutational burden (TMB), defined as the number of somatic mutations per megabase of interrogated genomic sequence, demonstrates predi......

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