Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH(+) Breast Cancer Stem Cells

Sarmiento-Castro, A; Caamano-Gutierrez, E; Sims, AH; Hull, NJ; James, MI; Santiago-Gomez, A; Eyre, R; Clark, C; Brown, ME; Brooks, MD; Wicha, MS; Howell, SJ; Clarke, RB; Simoes, BM

Clarke, RB; Simoes, BM (corresponding author), Univ Manchester, Div Canc Sci, Manchester Breast Ctr, Manchester M20 4GJ, Lancs, England.

STEM CELL REPORTS, 2020; 15 (2): 307

Abstract

Estrogen-receptor-positive breast tumors are treated with anti-estrogen (AE) therapies but frequently develop resistance. Cancer stem cells (CSCs) wit......

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