Microbubble drug conjugate and focused ultrasound blood brain barrier delivery of AAV-2 SIRT-3

Trinh, D; Nash, J; Goertz, D; Hynynen, K; Bulner, S; Iqbal, U; Keenan, J

Keenan, J (通讯作者),Artenga Inc, Ottawa, ON, Canada.

DRUG DELIVERY, 2022; 29 (1): 1176

Abstract

Background Delivery of viral vectors as gene therapies to treat neurodegenerative diseases has been hampered by the inability to penetrate the blood b......

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