Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus

Furie, R; Werth, VP; Merola, JF; Stevenson, L; Reynolds, TL; Naik, H; Wang, WT; Christmann, R; Gardet, A; Pellerin, A; Hamann, S; Auluck, P; Barbey, C; Gulati, P; Rabah, D; Franchimont, N

Rabah, D (reprint author), Biogen Inc, 225 Binney St, Cambridge, MA 02142 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2019; 129 (3): 1359

Abstract

BACKGROUND. Plasmacytoid DCs (pDC) produce large amounts of type I IFN (IFN-I), cytokines convincingly linked to systemic lupus erythematosus (SLE) pa......

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